The team at Sannie's Seeds created Mad Scientist (also known as Mad S.) as a combination of a White Widow female with a Herijuana male. It reportedly was named for a fellow grower, who helped Sannie's Seeds get started in the online cannabis industry.

The top reported aromas of the Mad Scientist strain are pungent coffee notes and slightly sweet lemon. And it is said to taste like coffee, lemon, and candied nuts.